Suitable reaction condition for preparation of Methyl phenyl ether is:
- A
Benzene, MeBr
- B
, MeOH
- C
Ph-Br,
- D
, MeBr
Suitable reaction condition for preparation of Methyl phenyl ether is:
Benzene, MeBr
, MeOH
Ph-Br,
, MeBr
Correct answer:D
Standard Method
Given: We need the suitable reaction condition for preparation of methyl phenyl ether.
Find: Which reagent pair gives by Williamson ether synthesis.
The Williamson ether synthesis involves reaction of an alkoxide or aryloxide ion with a primary alkyl halide.
For methyl phenyl ether, the required nucleophile is phenoxide ion and the alkyl halide must provide the methyl group.
The phenoxide ion acts as a nucleophile in an reaction and attacks methyl bromide to form the ether linkage.
Therefore, the correct option is D.
Note: the solution incorrectly labels the correct option as A, but its own reaction and explanation clearly support with MeBr, which is option D.
Choosing benzene with MeBr is incorrect because benzene does not directly form anisole under Williamson ether synthesis conditions. Use phenoxide ion as the nucleophile instead.
Using MeOH instead of MeBr is incorrect because an alcohol is not the proper electrophile for the ether-forming step. A primary alkyl halide such as MeBr is required.
Selecting Ph-Br with methoxide is incorrect because aryl halides do not undergo normal substitution at the aryl carbon. The alkyl halide should be methyl bromide, not bromobenzene.
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